Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system. We have previously shown that environmental toxins acting locally on the ENS mimic this PD-like pathology...

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Detalhes bibliográficos
Main Authors: Pan-Montojo, Francisco, Schwarz, Mathias, Winkler, Clemens, Arnhold, Mike, O'Sullivan, Gregory A., Pal, Arun, Said, Jonas, Marsico, Giovanni, Verbavatz, Jean-Marc, Rodrigo-Angulo, Margarita, Gille, Gabriele, Funk, Richard H. W., Reichmann, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510466/
https://ncbi.nlm.nih.gov/pubmed/23205266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00898
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