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Inhibition of GSK3 Abolishes Bacterial-Induced Periodontal Bone Loss in Mice

The tissue destruction that characterizes periodontitis is driven by the host response to bacterial pathogens. Inhibition of glycogen synthase kinase 3β (GSK3β) in innate cells leads to suppression of Toll-like receptor (TLR)-initiated proinflammatory cytokines under nuclear factor kappa-light-chain...

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Bibliografske podrobnosti
Main Authors: Adamowicz, Karina, Wang, Huizhi, Jotwani, Ravi, Zeller, Iris, Potempa, Jan, Scott, David A
Format: Artigo
Jezik:Inglês
Izdano: ScholarOne 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510296/
https://ncbi.nlm.nih.gov/pubmed/22847803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00180
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