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Inhibition of GSK3 Abolishes Bacterial-Induced Periodontal Bone Loss in Mice

The tissue destruction that characterizes periodontitis is driven by the host response to bacterial pathogens. Inhibition of glycogen synthase kinase 3β (GSK3β) in innate cells leads to suppression of Toll-like receptor (TLR)-initiated proinflammatory cytokines under nuclear factor kappa-light-chain...

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Detalhes bibliográficos
Main Authors: Adamowicz, Karina, Wang, Huizhi, Jotwani, Ravi, Zeller, Iris, Potempa, Jan, Scott, David A
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510296/
https://ncbi.nlm.nih.gov/pubmed/22847803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00180
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