Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis

Initial studies of 88 transmission pairs in the Zambia Emory HIV Research Project cohort demonstrated that the number of transmitted HLA-B associated polymorphisms in Gag, but not Nef, was negatively correlated to set point viral load (VL) in the newly infected partners. These results suggested that...

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Main Authors: Prince, Jessica L., Claiborne, Daniel T., Carlson, Jonathan M., Schaefer, Malinda, Yu, Tianwei, Lahki, Shabir, Prentice, Heather A., Yue, Ling, Vishwanathan, Sundaram A., Kilembe, William, Goepfert, Paul, Price, Matthew A., Gilmour, Jill, Mulenga, Joseph, Farmer, Paul, Derdeyn, Cynthia A., Tang, Jiaming, Heckerman, David, Kaslow, Richard A., Allen, Susan A., Hunter, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510241/
https://ncbi.nlm.nih.gov/pubmed/23209412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003041
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