A Trade-off between the Fitness Cost of Functional Integrases and Long-term Stability of Integrons

Horizontal gene transfer (HGT) plays a major role in bacterial microevolution as evident from the rapid emergence and spread of antimicrobial drug resistance. Few studies have however addressed the population dynamics of newly imported genetic elements after HGT. Here, we show that newly acquired cl...

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Bibliographic Details
Main Authors: Starikova, Irina, Harms, Klaus, Haugen, Pål, Lunde, Tracy T. M., Primicerio, Raul, Samuelsen, Ørjan, Nielsen, Kaare M., Johnsen, Pål J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510236/
https://ncbi.nlm.nih.gov/pubmed/23209414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003043
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