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Costly Class-1 integrons and the domestication of the the functional integrase

Class-1 integrons play an important role in the emergence and spread of antimicrobial resistance determinants. In a recent study we showed that host fitness was dramatically reduced following acquisition of these elements. These fitness costs were due to the presence of an active integrase and we su...

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Detalhes bibliográficos
Main Authors: Harms, Klaus, Starikova, Irina, Johnsen, Pål J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681742/
https://ncbi.nlm.nih.gov/pubmed/23914313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.24774
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