Uroporphyrinogen Decarboxylase as a Potential Target for Specific Components of Traditional Chinese Medicine: A Virtual Screening and Molecular Dynamics Study

Uroporphyrinogen decarboxylase (UROD) has been suggested as a protectant against radiation for head and neck cancer (HNC). In this study, we employed traditional Chinese medicine (TCM) compounds from TCM Database@Taiwan (http://tcm.cmu.edu.tw/) to screen for drug-like candidates with potential UROD...

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Detalhes bibliográficos
Main Authors: Tsou, Yung-An, Chen, Kuan-Chung, Lin, Hung-Che, Chang, Su-Sen, Chen, Calvin Yu-Chian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510221/
https://ncbi.nlm.nih.gov/pubmed/23209648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050087
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