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US28 Is a Potent Activator of Phospholipase C during HCMV Infection of Clinically Relevant Target Cells

Members of the cytomegalovirus family each encode two or more genes with significant homology to G-protein coupled receptors (GPCRs). In rodent models of pathogenesis, these viral encoded GPCRs play functionally significant roles, as their deletion results in crippled viruses that cannot traffic pro...

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Библиографические подробности
Главные авторы: Miller, William E., Zagorski, William A., Brenneman, Joanna D., Avery, Diana, Miller, Jeanette L. C., O’Connor, Christine M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510093/
https://ncbi.nlm.nih.gov/pubmed/23209769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050524
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