Corticosteroid-Induced Immunosuppression Ultimately Does Not Compromise the Efficacy of Antibiotherapy in Murine Mycobacterium ulcerans Infection

BACKGROUND: Buruli ulcer (BU) is a necrotizing disease of the skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. It has been suggested that the immune response developed during the recommended rifampicin/streptomycin (RS) antibiotherapy is protective, contributing to bacterial clea...

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Main Authors: Martins, Teresa G., Trigo, Gabriela, Fraga, Alexandra G., Gama, José B., Longatto-Filho, Adhemar, Saraiva, Margarida, Silva, Manuel T., Castro, António G., Pedrosa, Jorge
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510087/
https://ncbi.nlm.nih.gov/pubmed/23209864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001925
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