Local and Regional Re-Establishment of Cellular Immunity during Curative Antibiotherapy of Murine Mycobacterium ulcerans Infection

BACKGROUND: Buruli ulcer (BU) is a neglected necrotizing disease of the skin, subcutaneous tissue and bone, caused by Mycobacterium ulcerans. BU pathogenesis is associated with mycolactone, a lipidic exotoxin with cytotoxic and immunosuppressive properties. Since 2004, the World Health Organization...

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Detalhes bibliográficos
Main Authors: Martins, Teresa G., Gama, José B., Fraga, Alexandra G., Saraiva, Margarida, Silva, Manuel T., Castro, António G., Pedrosa, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290623/
https://ncbi.nlm.nih.gov/pubmed/22393444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032740
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