Mycobacterium ulcerans Triggers T-Cell Immunity followed by Local and Regional but Not Systemic Immunosuppression

Buruli ulcer is a neglected infectious disease caused by Mycobacterium ulcerans and is characterized by necrotic cutaneous lesions induced by the exotoxin mycolactone. Despite evidence of Th1-mediated protective immunity, M. ulcerans infection has been associated with systemic immunosuppression. We...

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Autori principali: Fraga, Alexandra G., Cruz, Andrea, Martins, Teresa G., Torrado, Egídio, Saraiva, Margarida, Pereira, Daniela R., Meyers, Wayne M., Portaels, Françoise, Silva, Manuel T., Castro, António G., Pedrosa, Jorge
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019874/
https://ncbi.nlm.nih.gov/pubmed/20974825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00820-10
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