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Lack of lipid phosphate phosphatase-3 in embryonic stem cells compromises neuronal differentiation and neurite outgrowth

Bioactive lipids such as lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) have been recently described as important regulators of pluripotency and differentiation of ES cells and neural progenitors. Here we show that LPP3, an enzyme that regulates the levels and biological activities of...

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Hlavní autoři: Sánchez-Sánchez, Roberto, Morales-Lázaro, Sara L., Baizabal, José-Manuel, Sunkara, Manjula, Morris, Andrew J., Escalante-Alcalde, Diana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509752/
https://ncbi.nlm.nih.gov/pubmed/22434721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23779
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