Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections

There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to the development of antisense Phosphorodiamidate Morpholino Oligomers (PMOs) AVI-6002 (composed of AVI-7357 and AVI-7539) and AVI-6003 (composed of AVI-7287 and AVI-7288) ta...

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Detalhes bibliográficos
Main Authors: Iversen, Patrick L., Warren, Travis K., Wells, Jay B., Garza, Nicole L., Mourich, Dan V., Welch, Lisa S., Panchal, Rekha G., Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509674/
https://ncbi.nlm.nih.gov/pubmed/23202506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v4112806
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