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Detection of Glycomic Alterations Induced by Overexpression of P-Glycoprotein on the Surfaces of L1210 Cells Using Sialic Acid Binding Lectins

P-glycoprotein (P-gp) overexpression is the most frequently observed cause of multidrug resistance in neoplastic cells. In our experiments, P-gp was expressed in L1210 mice leukemia cells (S cells) by selection with vincristine (R cells) or transfection with the gene encoding human P-gp (T cells). R...

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Main Authors: Bubencíkova, Tatiana, Cholujová, Dana, Messingerová, Lucia, Mislovicova, Danica, Seres, Mario, Breier, Albert, Sulova, Zdena
格式: Artigo
語言:Inglês
出版: Molecular Diversity Preservation International (MDPI) 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509634/
https://ncbi.nlm.nih.gov/pubmed/23203118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131115177
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