The Effect of Glycyrrhetinic Acid on Pharmacokinetics of Cortisone and Its Metabolite Cortisol in Rats

The purpose of this paper is to study pharmacokinetics of cortisone (E) and its metabolite cortisol (F) in rats after administration of glycyrrhetinic acid (GA) and cortisone. Healthy male SD rats were randomized to be given 20 mg/kg E or E combined with 10 mg/kg GA. Blood samples were collected at...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Dan, Sun, Wei, Wang, Zhe, Chen, Lian-Guo, Chen, Xiao-Le, Wang, Shuang-Hu, Li, Wan-Shu, Ge, Ren-Shan, Hu, Guo-Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509542/
https://ncbi.nlm.nih.gov/pubmed/23258958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/856324
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