The Average IFN-γ Secreting Capacity of Specific CD8(+) T Cells Is Compromised While Increasing Copies of a Single T Cell Epitope Encoded by DNA Vaccine

Previous studies suggested that both the frequency and the mean fluorescence intensity (MFI) of cytokine secreting T cells could be of great value for immunogenicity evaluation of a vaccine. In this study, by constructing epitope-based DNA vaccines encoding a previously identified CD8(+) T cell epit...

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Main Authors: Wan, Yanmin, Wang, Jing, Zhou, Haizhu, Hu, Zhidong, Ren, Xiaonan, Xu, Jianqing
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509377/
https://ncbi.nlm.nih.gov/pubmed/23251217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/478052
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