Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

Glioblastoma (GBM) is the most common primary brain tumor in adults and has a dismal prognosis despite multimodality treatment. Given the resistance of glioma stem cells (GSC) to chemotherapy and radiation therapy, their eradication could prevent tumor recurrence. We sought to evaluate the antitumor...

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Main Authors: Allen, Cory, Opyrchal, Mateusz, Aderca, Ileana, Schroeder, Mark A., Sarkaria, Jann N., Domingo, Evidio, Federspiel, Mark J., Galanis, Evanthia
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509233/
https://ncbi.nlm.nih.gov/pubmed/22914495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.62
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