Interleukin-13 Displaying Retargeted Oncolytic Measles Virus Strains Have Significant Activity Against Gliomas With Improved Specificity

The majority of glioblastoma multiforme (GBM) tumors (80%) overexpress interleukin-13 receptor α2 (IL-13Rα2), but there is no expression of IL-13Rα2 in normal brain. Vaccine strains of measles virus have significant antitumor activity against gliomas. We tested the hypothesis that measles virus entr...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Allen, Cory, Paraskevakou, Georgia, Iankov, Ianko, Giannini, Caterina, Schroeder, Mark, Sarkaria, Jann, Puri, Raj K, Russell, Stephen J, Galanis, Evanthia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748750/
https://ncbi.nlm.nih.gov/pubmed/18665158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.152
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