Improving Protein Identification Sensitivity by Combining MS and MS/MS Information for Shotgun Proteomics Using LTQ-Orbitrap High Mass Accuracy Data

We investigated and compared three approaches for shotgun protein identification by combining MS and MS/MS information using LTQ-Orbitrap high mass accuracy data. In the first approach, we employed a unique mass identifier method where MS peaks matched to proteins identified from an MS/MS database s...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Bingwen, Motoyama, Akira, Ruse, Cristian, Venable, John, Yates, John R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509208/
https://ncbi.nlm.nih.gov/pubmed/18275164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac701697w
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