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A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk
BACKGROUND: The mTOR signaling pathway plays a crucial role in the carcinogenesis of renal cell cancer (RCC). We sought to investigate the influence of genetic variations in the mTOR pathway-related genes on the risk of RCC. METHODS: We genotyped 8 potentially functional polymorphisms in AKT1, AKT2,...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508984/ https://ncbi.nlm.nih.gov/pubmed/23209702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050302 |
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