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Functional Promoter -31G>C Variant in Survivin Gene Is Associated with Risk and Progression of Renal Cell Cancer in a Chinese Population

BACKGROUND: Survivin is an inhibitor of apoptosis protein and is involved in the occurrence and progression of human malignancies. Recently, a functional polymorphism (−31G>C, rs9904341) in the promoter of survivin has been shown to influence its expression and confer susceptibility to different...

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Detalhes bibliográficos
Main Authors: Qin, Chao, Cao, Qiang, Li, Pu, Ju, Xiaobing, Wang, Meilin, Chen, Jiawei, Wu, Yilong, Meng, Xiaoxin, Zhu, Jian, Zhang, Zhengdong, Lu, Qiang, Yin, Changjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266235/
https://ncbi.nlm.nih.gov/pubmed/22295057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028829
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