Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

BACKGROUND: (18)F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atherosclerosis in the clinic is based on preferential accumulation of radioactive glucose analog in atherosclerotic plaques. FDG-PET is challenging in mouse models due to limited resolution and high cost. We ai...

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Detalhes bibliográficos
Main Authors: Conway, Richard G., Chernet, Eyassu, De Rosa, David C., Benschop, Robert J., Need, Anne B., Collins, Emily C., Bean, James S., Kalbfleisch, J. Michael, Rekhter, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508896/
https://ncbi.nlm.nih.gov/pubmed/23209718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050349
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