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The Anti-tumor Effects of Adenoviral-Mediated, Intra-tumoral delivery Interleukin 23 require Endogenous IL-12

IL-23 is a member of the IL-12 family of heterodimeric cytokines, comprised of p19 and p40 subunits, which exhibits immunostimulatory properties similar to IL-12. We have demonstrated previously that adenoviral-mediated, intra-tumoral delivery of IL-23 (Ad.IL-23) was able to induce systemic anti-tum...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Reay, Ja’Nean, Gambotto, Andrea, Robbins, Paul D.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508719/
https://ncbi.nlm.nih.gov/pubmed/22158522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2011.78
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