An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis

Details of metastasis, the deadliest aspect of cancer, are unclear. Cell surface proteins play central roles in adhesive contacts between the tumor cell and the stroma during metastasis. We optimized a fast, small-scale isolation of biotinylated cell surface proteins to reveal novel metastasis-assoc...

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Hauptverfasser: Karhemo, Piia-Riitta, Ravela, Suvi, Laakso, Marko, Ritamo, Ilja, Tatti, Olga, Mäkinen, Selina, Goodison, Steve, Stenman, Ulf-Håkan, Hölttä, Erkki, Hautaniemi, Sampsa, Valmu, Leena, Lehti, Kaisa, Laakkonen, Pirjo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508169/
https://ncbi.nlm.nih.gov/pubmed/22813880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.07.009
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