An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis

Details of metastasis, the deadliest aspect of cancer, are unclear. Cell surface proteins play central roles in adhesive contacts between the tumor cell and the stroma during metastasis. We optimized a fast, small-scale isolation of biotinylated cell surface proteins to reveal novel metastasis-assoc...

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Main Authors: Karhemo, Piia-Riitta, Ravela, Suvi, Laakso, Marko, Ritamo, Ilja, Tatti, Olga, Mäkinen, Selina, Goodison, Steve, Stenman, Ulf-Håkan, Hölttä, Erkki, Hautaniemi, Sampsa, Valmu, Leena, Lehti, Kaisa, Laakkonen, Pirjo
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508169/
https://ncbi.nlm.nih.gov/pubmed/22813880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.07.009
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