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Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

NAD(P)H:quinone reductase 1 (QR1) belongs to a class of enzymes called cytoprotective enzymes. It exhibits its cancer protective activity mainly by inhibiting the formation of intracellular semiquinone radicals, and by generating α-tocopherolhydroquinone, which acts as a free radical scavenger. It i...

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Библиографические подробности
Главные авторы: Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508077/
https://ncbi.nlm.nih.gov/pubmed/23142320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.10.006
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