Rap1 Can Bypass the FAK-Src-Paxillin Cascade to Induce Cell Spreading and Focal Adhesion Formation

We developed new image analysis tools to analyse quantitatively the extracellular-matrix-dependent cell spreading process imaged by live-cell epifluorescence microscopy. Using these tools, we investigated cell spreading induced by activation of the small GTPase, Rap1. After replating and initial adh...

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Detalhes bibliográficos
Main Authors: Ross, Sarah H., Spanjaard, Emma, Post, Anneke, Vliem, Marjolein J., Kristyanto, Hendy, Bos, Johannes L., de Rooij, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507925/
https://ncbi.nlm.nih.gov/pubmed/23209645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050072
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