Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53

The tumor suppressor protein p53 has been described “as the guardian of the genome” for its crucial role in regulating the transcription of numerous genes responsible for cells cycle arrest, senescence, or apoptosis in response to various stress signals. Although p53 promotes longevity by decreasing...

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Detalhes bibliográficos
Main Authors: Fiorini, Ada, Sultana, Rukhsana, Barone, Eugenio, Cenini, Giovanna, Perluigi, Marzia, Mancuso, Cesare, Cai, Jian, Klein, Jon B., St. Clair, Daret, Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507874/
https://ncbi.nlm.nih.gov/pubmed/23209608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049846
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