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Identifying mutation regions for closely related individuals without a known pedigree
BACKGROUND: Linkage analysis is the first step in the search for a disease gene. Linkage studies have facilitated the identification of several hundred human genes that can harbor mutations leading to a disease phenotype. In this paper, we study a very important case, where the sampled individuals a...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507658/ https://ncbi.nlm.nih.gov/pubmed/22731852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-146 |
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