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A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals

Cells perceive a wide variety of cellular and environmental signals, which are often processed combinatorially to generate particular phenotypic responses. Here, we employ both single and mixed cell type populations, pre-programmed with engineered modular cell signalling and sensing circuits, as pro...

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Autors principals: Wang, Baojun, Barahona, Mauricio, Buck, Martin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Advanced Technology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507625/
https://ncbi.nlm.nih.gov/pubmed/22981411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2012.08.011
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