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Engineering modular and tunable genetic amplifiers for scaling transcriptional signals in cascaded gene networks

Synthetic biology aims to control and reprogram signal processing pathways within living cells so as to realize repurposed, beneficial applications. Here we report the design and construction of a set of modular and gain-tunable genetic amplifiers in Escherichia coli capable of amplifying a transcri...

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Detalhes bibliográficos
Main Authors: Wang, Baojun, Barahona, Mauricio, Buck, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132719/
https://ncbi.nlm.nih.gov/pubmed/25030903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku593
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