Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3(+) Regulatory T Cells via Integrin αvβ8

BACKGROUND & AIMS: The intestinal immune system is tightly regulated to prevent responses against the many nonpathogenic antigens in the gut. Transforming growth factor (TGF)-β is a cytokine that maintains intestinal homeostasis, in part by inducing Foxp3(+) regulatory T cells (Tregs) that suppr...

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Detalhes bibliográficos
Main Authors: Worthington, John J., Czajkowska, Beata I., Melton, Andrew C., Travis, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507624/
https://ncbi.nlm.nih.gov/pubmed/21723222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.057
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