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CaMKII activation and dynamics are independent of holoenzyme structure: an infinite subunit holoenzyme approximation
The combinatorial explosion produced by the multi-state, multi-subunit character of CaMKII has made analysis and modeling of this key signaling protein a significant challenge. Using rule-based and particle-based approaches, we construct exact models of CaMKII holoenzyme dynamics and study these mod...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507550/ https://ncbi.nlm.nih.gov/pubmed/22683827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/9/3/036010 |
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