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Glucose—a sweet way to die: Metabolic switching modulates tumor cell death

TRAIL, a putative anticancer cytokine, induces extrinsic cell death by activating the caspase cascade directly (Type I cells) via the death-inducing signaling complex (DISC) or indirectly (Type II cells) by caspase-8 cleavage of Bid and activation of the mitochondrial cell death pathway. Cancer cell...

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Detalhes bibliográficos
Main Authors: MacFarlane, Marion, Robinson, Gemma L., Cain, Kelvin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507486/
https://ncbi.nlm.nih.gov/pubmed/22983094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21804
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