Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels

BACKGROUND: Heart failure is associated with abnormalities of myocardial structure, and plasma levels of the advanced glycation end-product (AGE) N(ε)-(carboxymethyl)lysine (CML) correlate with the severity and prognosis of heart failure. Aging is associated with diastolic dysfunction and increased...

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Detalhes bibliográficos
Main Authors: Campbell, Duncan J., Somaratne, Jithendra B., Jenkins, Alicia J., Prior, David L., Yii, Michael, Kenny, James F., Newcomb, Andrew E., Schalkwijk, Casper G., Black, Mary Jane, Kelly, Darren J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506639/
https://ncbi.nlm.nih.gov/pubmed/23189164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049813
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