Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection

BACKGROUND: Regulation of immune responses is critical for controlling inflammation and disruption of this process can lead to tissue damage. We reported that CXCL13 was induced in fallopian tube tissue following C. trachomatis infection. Here, we examined the influence of the CXCL13-CXCR5 axis in c...

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Hauptverfasser: Jiang, Janina, Karimi, Ouafae, Ouburg, Sander, Champion, Cheryl I., Khurana, Archana, Liu, Guangchao, Freed, Amanda, Pleijster, Jolein, Rozengurt, Nora, Land, Jolande A., Surcel, Helja-Marja, Tiitinen, Aila', Paavonen, Jorma, Kronenberg, Mitchell, Morré, Servaas A., Kelly, Kathleen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506621/
https://ncbi.nlm.nih.gov/pubmed/23189125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047487
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