Mitochondrial Localization of ABC Transporter ABCG2 and Its Function in 5-Aminolevulinic Acid-Mediated Protoporphyrin IX Accumulation

Accumulation of protoporphyrin IX (PpIX) in malignant cells is the basis of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy. We studied the expression of proteins that possibly affect ALA-mediated PpIX accumulation, namely oligopeptide transporter-1 and -2, ferrochelatase and ATP-binding c...

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Detalhes bibliográficos
Main Authors: Kobuchi, Hirotsugu, Moriya, Koko, Ogino, Tetsuya, Fujita, Hirofumi, Inoue, Keiji, Shuin, Taro, Yasuda, Tatsuji, Utsumi, Kozo, Utsumi, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506543/
https://ncbi.nlm.nih.gov/pubmed/23189181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050082
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