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Effects of Molecular Crowding on the Dynamics of Intrinsically Disordered Proteins

Inside cells, the concentration of macromolecules can reach up to 400 g/L. In such crowded environments, proteins are expected to behave differently than in vitro. It has been shown that the stability and the folding rate of a globular protein can be altered by the excluded volume effect produced by...

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Bibliografiska uppgifter
Huvudupphovsmän: Cino, Elio A., Karttunen, Mikko, Choy, Wing-Yiu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506533/
https://ncbi.nlm.nih.gov/pubmed/23189168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049876
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