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The potential for selective pharmacological therapies through biased receptor signaling

The discovery that not all agonists uniformly activate cellular signaling pathways (biased signaling) has greatly changed the drug discovery process for agonists and the strategy for treatment of disease with agonists. Technological advances have enabled complex receptor behaviors to be viewed indep...

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Библиографические подробности
Главный автор: Kenakin, Terry
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506267/
https://ncbi.nlm.nih.gov/pubmed/22947056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-3
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