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The potential for selective pharmacological therapies through biased receptor signaling

The discovery that not all agonists uniformly activate cellular signaling pathways (biased signaling) has greatly changed the drug discovery process for agonists and the strategy for treatment of disease with agonists. Technological advances have enabled complex receptor behaviors to be viewed indep...

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Hlavní autor: Kenakin, Terry
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506267/
https://ncbi.nlm.nih.gov/pubmed/22947056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-3
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