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Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior
Childhood trauma is associated with hypothalamic–pituitary–adrenal (HPA) axis dysregulation. Both factors increase risk for suicidal behavior. Corticotropin releasing hormone (CRH) regulates the HPA axis and its actions are moderated by a high-affinity binding protein (CRHBP). We hypothesized that C...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506169/ https://ncbi.nlm.nih.gov/pubmed/21978546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2011.09.009 |
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