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The Influence of GABRA2, Childhood Trauma and their Interaction on Alcohol, Heroin and Cocaine Dependence

BACKGROUND: The GABRA2 gene has been implicated in addiction. Early life stress has been shown to alter GABRA2 expression in adult rodents. We hypothesized that childhood trauma, GABRA2 variation and their interaction would influence addiction vulnerability. METHODS: African American men were recrui...

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Autori principali: Enoch, Mary-Anne, Hodgkinson, Colin A, Yuan, Qiaoping, Shen, Pei-Hong, Goldman, David, Roy, Alec
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964936/
https://ncbi.nlm.nih.gov/pubmed/19833324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.019
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