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Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression
LacI/GalR transcription regulators have extensive, non-conserved interfaces between their regulatory domains and the 18 amino acids that serve as ‘linkers’ to their DNA-binding domains. These non-conserved interfaces might contribute to functional differences between paralogs. Previously, two chimer...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505978/ https://ncbi.nlm.nih.gov/pubmed/22965134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks806 |
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