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In Search of Cathepsins: How Reovirus Enters Host Cells

Encapsidated viruses bind cell surface receptors and enter through receptor-mediated endocytosis. The next step in infection requires uncoating of the virion. In this inaugural BIT, the role of proteases of the Cathepsin family, which are found endosomes, are critical for viral replication.

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Bibliographische Detailangaben
Hauptverfasser: Mainou, Bernardo A., Dermody, Terence S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505829/
https://ncbi.nlm.nih.gov/pubmed/23134451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1868
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