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In Search of Cathepsins: How Reovirus Enters Host Cells

Encapsidated viruses bind cell surface receptors and enter through receptor-mediated endocytosis. The next step in infection requires uncoating of the virion. In this inaugural BIT, the role of proteases of the Cathepsin family, which are found endosomes, are critical for viral replication.

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Bibliografske podrobnosti
Main Authors: Mainou, Bernardo A., Dermody, Terence S.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505829/
https://ncbi.nlm.nih.gov/pubmed/23134451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1868
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