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The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H(2)O(2) and Plays an Integral Role in Insulin Signal Transduction
Insulin stimulation of target cells elicits a burst of H(2)O(2) that enhances tyrosine phosphorylation of the insulin receptor and its cellular substrate proteins as well as distal signaling events in the insulin action cascade. The molecular mechanism coupling the insulin receptor with the cellular...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC350558/ https://ncbi.nlm.nih.gov/pubmed/14966267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1844-1854.2004 |
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