The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H(2)O(2) and Plays an Integral Role in Insulin Signal Transduction

Insulin stimulation of target cells elicits a burst of H(2)O(2) that enhances tyrosine phosphorylation of the insulin receptor and its cellular substrate proteins as well as distal signaling events in the insulin action cascade. The molecular mechanism coupling the insulin receptor with the cellular...

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Bibliografiset tiedot
Päätekijät: Mahadev, Kalyankar, Motoshima, Hiroyuki, Wu, Xiangdong, Ruddy, Jean Marie, Arnold, Rebecca S., Cheng, Guangjie, Lambeth, J. David, Goldstein, Barry J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Cell Growth and Development
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC350558/
https://ncbi.nlm.nih.gov/pubmed/14966267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1844-1854.2004
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