LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

BACKGROUND: The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic mutations target similar genes and pathways. We hypothesize that during carcinogenesis, certain pathways or biological gene sets...

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Bibliographic Details
Main Authors:	Kim, Jung H, Karnovsky, Alla, Mahavisno, Vasudeva, Weymouth, Terry, Pande, Manjusha, Dolinoy, Dana C, Rozek, Laura S, Sartor, Maureen A
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2012
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3505188/ https://ncbi.nlm.nih.gov/pubmed/23033966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-526
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LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

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