LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

BACKGROUND: The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic mutations target similar genes and pathways. We hypothesize that during carcinogenesis, certain pathways or biological gene sets...

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Main Authors: Kim, Jung H, Karnovsky, Alla, Mahavisno, Vasudeva, Weymouth, Terry, Pande, Manjusha, Dolinoy, Dana C, Rozek, Laura S, Sartor, Maureen A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505188/
https://ncbi.nlm.nih.gov/pubmed/23033966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-526
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