Short Communication: HIV Type 1 Escapes Inactivation by Saliva via Rapid Escape into Oral Epithelial Cells

Saliva contains anti-HIV-1 factors, which show unclear efficacy in thwarting mucosal infection. When incubated in fresh, unfractionated whole saliva, infectious HIV-1 IIIb and BaL (X4- and R5-tropic, respectively) persisted from 4 to at least 30 min in a saliva concentration-dependent manner. In sal...

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Detalhes bibliográficos
Main Authors: Dietrich, Elizabeth A., Gebhard, Kristin H., Fasching, Claudine E., Giacaman, Rodrigo A., Kappes, John C., Ross, Karen F., Herzberg, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505059/
https://ncbi.nlm.nih.gov/pubmed/22077822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2011.0069
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